Covariate-adaptive randomization represents an advanced methodology in the design of clinical trials, ensuring a balanced distribution of prognostic factors among treatment groups. This approach ...

The equipoise randomization strategy allowed patients to indicate a preference to which of the level 2 options they would accept or refuse. Only 1% of the cohort would accept all 7 treatment options.

In an ongoing international, multifactorial, adaptive platform, randomized, controlled trial, we evaluated simvastatin (80 mg daily) as compared with no statin (control) in critically ill patients ...

Randomization Techniques (60 minutes): In this workshop, the rationale behind randomized experiments will be explained. Descriptions of commonly utilized randomization algorithms will be presented, ...

The CORE-MD (Coordinating Research and Evidence for high-risk Medical Devices) consortium has published new consensus ...

Peer review and the editorial process yield frequent improvements in research abstracts of randomized clinical trial (RCT) ...

Identification of a Suitable Subgroup for Radiation Dose Escalation in Definitive Concurrent Chemoradiation Therapy for Nonmetastatic Esophageal Squamous Cell Carcinoma The median follow-up for ...

An international group of researchers has developed a new tool that can help identify problematic randomized controlled ...

Peer review and the editorial process yield frequent improvements in research abstracts of randomized clinical trial reports, data suggest.

Twice-yearly subcutaneous lenacapavir has been shown to be efficacious for prevention of human immunodeficiency virus (HIV) infection in cisgender women. The efficacy of lenacapavir for preexposure ...