Researchers have described a large set of previously unrecognized enzymatic domains—named the Lipocone superfamily—and outlined their evolutionary pathway from bacterial defense molecules to key ...

A protein historian and evolutionary biochemist found that a protein sequence present across all known life didn’t form as ...

Researchers have described a large set of previously unrecognized enzymatic domains – named the Lipocone superfamily – and outlined their evolutionary pathway from bacterial defense molecules to key ...

The molecule Wnt, which plays a role in cell communication during human development, evolved from a superfamily with a shared lipid-modifying mechanism originally involved in bacterial defence and ...

To solve a problem, we have to see it clearly. Whether it's an infection by a novel virus or memory-stealing plaques forming ...

While our understanding of Alzheimer’s disease is far from complete, the latest therapies, and others in more than 100 ...

Although proteins are inherently dynamic, they have typically been depicted as static molecules. Advances in experimental and ...

Alzheimer’s disease has proved to be a tricky target, and researchers and drug developers have been pursuing effective treatments for decades. The brains of people who die with Alzheimer’s show a ...

MP, which was found to play a critical role in upholding mitochondrial structure and regulating metabolic stress in mouse fat cells.

Scientists in Korea have engineered magnetic nanohelices that can control electron spin with extraordinary precision at room ...

Understanding how fat molecules are organised and function in living organisms is essential to reveal mechanisms of ageing, ...