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震惊!Cancer Discov:常见甜味剂蔗糖素竟会削弱癌症免疫治疗效果
关键验证实验显示,补充精氨酸或其前体瓜氨酸,能有效恢复 T 细胞的细胞毒性功能和代谢活性,使蔗糖素喂养小鼠重新对 PD-1 抑制剂产生响应,显著延长生存期。这一发现为临床干预提供了明确靶点 —— 瓜氨酸补充可使肿瘤内 IFNγ+ T ...
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