RNA-binding proteins use a dual binding mechanism involving zinc finger (ZnF) domains and intrinsically disordered regions (IDR), reports a new study from the Institute of Science, Tokyo, Japan. Using ...

For some cultures, the practice of cranial deformation may have offered individuals a path to privilege later in their lives. The elongated skull of a person who lived in the Colca Valley of highland ...

The Canadian government brought the Air Canada strike to a screeching halt Saturday by imposing binding arbitration on the airline and its flight attendants. The move came less than 12 hours after Air ...

Triple-negative breast cancer (TNBC) lacks the expression of hormone and HER2 receptors and is highly malignant with no effective therapeutic targets. In TNBC, the cancer stem-like cell (CSC) ...

Abstract: The identification of protein-peptide interacting pairs and their corresponding binding residues is fundamentally crucial and can greatly facilitate the peptide therapeutics designing and ...

A local North Jersey manufacturer and a banking giant are laying off nearly 200 people combined in the coming weeks, according to public notices filed with the New Jersey Department of Labor. The ...

YBX1 is a member of the Y-box transcription factor family and is a multifunctional RNA/DNA-binding protein characterized by a highly conserved cold shock domain (CSD). YBX1 is localized in both the ...

The original version of this story appeared in Quanta Magazine. When Todd Sacktor was about to turn 3, his 4-year-old sister died of leukemia. “An empty bedroom next to mine. A swing set with two ...

Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University, Richmond, Virginia 23298, United States The Center for Drug Discovery, Virginia Commonwealth University, ...