In patients with hematological malignancies receiving HLA-matched stem cell transplantation, T cells specific for minor histocompatibility antigens play a major role in graft rejection, induction of ...

Although experimental protocols in mice are revealing the potential of immunotherapy in cancer treatment, successful vaccination strategies in cancer patients are wanting. One possible explanation is ...

Complementary DNA (cDNA) libraries are standard tools for gene expression studies. In theory, the library contains full-length DNA copies of every mRNA in the starting sample, in abundances ...

Vol. 17, Supplement 5: Research from the National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, and Charles R. Drew University of Medicine and Science 2006 ...

The root hair is a specialized cell type involved in water and nutrient uptake in plants. In legumes the root hair is also the primary site of recognition and infection by symbiotic nitrogen-fixing ...

Core laboratories must balance the efficiency of their NGS workflow with the quality of the data that they produce in providing numerous next generation sequencing (NGS) services relating to a wide ...

A new review in eGastroenterology highlights how single-cell transcriptomics is revolutionizing our understanding of acute ...

Geneticists subject to late-night bouts of inspiration generally have to write down their good ideas. It's not as if you could just walk across the room, get the gene you need for your experiment, and ...

What is an RNA sequencing library? In all RNA-seq experiments, a library of cDNA fragments attached to adapters must be synthesized in order for sequencing to be successful. How do you prepare an RNA ...

RNAConnect, a leader in next-generation molecular biology tools, today announced the commercial launch of the UltraMarathonRT cDNA Synthesis and Amplification Kit, designed to elevate short-read RNA ...