There are many valid ways to do this, but my first choice is Web2Py, a relatively easy to use open-source framework for developing web applications in Python.

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Reflex has built an open source framework to make it easy to turn Python code into a we app. Today it announced a $5M seed investment.

The code is on GitHub and he also links to the generators available in SciPy. We’ve seen SciPy in some Hackaday contest entries before. You can think of it like Matlab for Python.