Zongertinib in HER2-altered breast cancer: Preclinical activity and preliminary results from a phase Ia dose-escalation study. This is an ASCO Meeting Abstract from the 2025 ASCO Annual Meeting I.

Representative images and heatmaps illustrate how human fetal tooth germs from the upper and lower jaws, although morphologically similar at the cap stage, already display distinct gene expression ...

Genetic configurations and liver niche drive tumor-intrinsic state plasticity in metastatic MSS-CRC. This is an ASCO Meeting Abstract from the 2026 ASCO Gastrointestinal Cancers Symposium. This ...

While endothelial cells (ECs) are pivotal in vascular development, the chromatin dynamics governing human EC specification remain elusive due to limited access to embryonic models. Here, we ...

Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...

A high-throughput workflow integrates DNA methylation and RNA sequencing in single cells, enabling more complete insights ...

Knowing the location of a gene within intact tissue or a single cell allows scientists to unlock unknown cellular functions. This information is often lost in most genetic sequencing techniques, but ...

Morgan Hiebert (left) studies drug-resistant tuberculosis within the National Reference Centre for Mycobacteriology (Winnipeg, Manitoba) led by Hafid Soualhine, situated in the National Microbiology ...

An integrative Translational Psychiatry study linked BPA exposure to major depressive disorder by identifying 571 shared ...