Gut microbiome composition in active colitis and treatment-induced remission with in vivo functional validation of pro-inflammatory activity in gnotobiotic TRUC mice.

One patient (#7) in this study had normal surfactant composition and function, despite two mutations that had a high probability of significantly disrupting protein expression and/or function.

The problem of minimizing a concave function subject to linear inequality constraints may have many local solutions. Therefore, finding the global constrained minimum is a computationally difficult ...